Ipamorelin + Tesamorelin Stack Protocol

GHRP + GHRH together is the most effective way to raise your own growth hormone. Ipamorelin tells the pituitary "release GH," tesamorelin tells it "produce more and release." Together, GH output is 2-3x higher than either alone. Here's the ready protocol.

Why stack instead of solo

[[Ipamorelin|17]] (GHRP) binds ghrelin receptors and triggers a GH pulse. But it works with however much GH the pituitary has already made. [[Tesamorelin|18]] (GHRH) stimulates the pituitary to produce more GH, increasing the available pool.

When you inject both simultaneously, tesamorelin fills the GH "reservoir" and ipamorelin opens the "tap." Result: significantly stronger pulse with a higher peak and longer elevation.

Ready protocol

Doses: Ipamorelin 200-300mcg + Tesamorelin 1-2mg, both subcutaneous, same session.

Schedule: Twice daily. Morning fasted (2+ hours without food). Pre-bed (2+ hours after last meal). Evening dose synergizes with natural nocturnal GH peak.

Duration: 8-12 weeks, then 4 weeks off. Break prevents ghrelin receptor desensitization.

Nutrition: Carbs and fats blunt GH release. Dose strictly fasted. Protein snack is acceptable.

Expected effects

• Body composition improvement (less fat, more lean mass) by week 4-6
• Deeper sleep from week 1 (especially evening dose)
• Faster recovery between training sessions
• Skin and hair quality improvement (GH collagen effect) by week 6-8

Side effects

Light head rush after injection (GH pulse), occasional water retention in first 1-2 weeks. No cortisol, no prolactin, no extreme hunger. If you get tingling in hands (carpal tunnel), reduce tesamorelin dose.

Need help with dosing? Reach out to us.

This article is for educational purposes. Peptides are intended for research use. Consult a healthcare professional before starting any protocol.