Buy Ipamorelin — Growth Hormone Secretagogue
Ipamorelin is a selective pentapeptide growth-hormone secretagogue (GHS) and ghrelin-receptor (GHSR-1a) agonist that was originally developed in the late 1990s as a tool to study growth-hormone release without the off-target effects of earlier GHS molecules. Unlike GHRP-6 or hexarelin, ipamorelin binds the ghrelin receptor with high selectivity and does not appreciably raise cortisol, prolactin, or aldosterone at research doses, which is why it is widely used in laboratory studies of the somatotropic axis.Mechanism of actionIpamorelin mimics ghrelin at the GHSR-1a receptor on somatotroph cells in the anterior pituitary, triggering a pulsatile release of endogenous growth hormone. Because the secretion is pulsatile, it preserves the body's natural feedback loop with IGF-1, unlike recombinant HGH, which delivers a sustained non-physiological signal. Ipamorelin is commonly paired with a growth-hormone-releasing hormone analogue such as CJC-1295 or Tesamorelin to study synergistic GH release.Evidence from peer-reviewed researchThe peptide was first characterised in the European Journal of Endocrinology in 1998 as "the first selective GHS" with a clean side-effect profile in rodents. A 1999 paper in Growth Hormone & IGF Research showed that ipamorelin induces longitudinal bone growth in rats, confirming its downstream IGF-1-mediated effects. Subsequent work has focused on tissue-repair outcomes and potential applications in sarcopenia research.Typical research protocolsIn laboratory studies, ipamorelin is commonly administered subcutaneously in micrograms-per-kilogram doses, once or twice daily, on an empty stomach to avoid competing with dietary amino-acid interference on GH release. Combination protocols with CJC-1295 (no-DAC) are frequent in research contexts that aim to map the timing and amplitude of GH pulses.Quality and purityPEPTEX ipamorelin is manufactured to ≥99% purity, verified by HPLC and mass spectrometry, and lyophilised into vials with certificates of analysis available on request.Storage and handlingStore lyophilised ipamorelin at −20 °C in the dark, where it is stable for up to 24 months. After reconstitution with bacteriostatic water, store at 2–8 °C and use within 12 weeks.
Price: EUR 59.00 | Brand: PEPTEX | In Stock | EU-wide delivery, 3-5 business days
Rating: 4.8/5 (160 reviews)
Customer Reviews
linn.s — ★★★★
solid GH peptide without the mess of GHRP-6 (no hunger spikes, no cortisol). been using ipamorelin for three 8-week cycles now with consistent results. recovery between leg days is noticeably faster. peptex quality has been the same every time
Eloise — ★★★★
Good product, slightly inconvenient dosing schedule (fasted 2x daily). The results justify the effort though. My naturopath noticed improvements in my skin and recovery markers. Quality from peptex is consistent.
Alejandro M. — ★★★★★
Combined with tesa as the GHRP+GHRH stack. The synergy is documented and I can confirm it from my IGF-1 lab work. Both from peptex, both excellent quality. Support actually understood the stacking logic when I asked.
george_93 — ★★★★★
Sleep changed within the first three nights. Not just duration but depth. My Garmin shows body battery scores 15-20 points higher every morning. Running 200mcg before bed, empty stomach. The pre-bed GH pulse amplification is real and measurable.
Manon K. — ★★★★
Works well but I notice the effects fade quickly during the off-cycle. Within 2-3 weeks of stopping, sleep depth returns to baseline. That's the nature of the compound, not a quality issue. Peptex product is excellent.
Available Sizes
- 5mg — 59 EUR
Storage Recommendations
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 12 weeks with bacteriostatic water |
Research References
- Ipamorelin, the first selective growth hormone secretagogue — Eur J Endocrinol / PubMed (1998)
- Ipamorelin induces longitudinal bone growth in rats — Growth Horm IGF Res / PubMed (1999)
Frequently Asked Questions
What is Ipamorelin and how does it stimulate growth hormone production?
Ipamorelin is a peptide from the growth hormone secretagogue (GHRP) group that acts on ghrelin receptors (GHS-R1a) in the pituitary gland. It stimulates the body's own growth hormone production without significantly raising cortisol and prolactin levels — which distinguishes it from other secretagogues. Ipamorelin increases insulin-like growth factor-1 (IGF-1) levels, which affects recovery processes, metabolism, and overall health.
How to properly take Ipamorelin and what to combine it with?
Ipamorelin is administered subcutaneously daily at a dosage of 0.25–0.5 mg. The optimal injection time is before bedtime, with food avoided for at least 2 hours before injection for maximum growth hormone stimulation. The course lasts 2–12 weeks. Ipamorelin is most effective when combined with Tesamorelin — their combined use provides a synergistic effect, as they stimulate growth hormone through different receptor pathways.
What benefits does an Ipamorelin course provide?
An Ipamorelin course promotes: increased protein synthesis and muscle mass growth, reduced body fat and improved body composition, faster recovery after workouts and injuries, improved sleep quality and increased overall energy, strengthened bone tissue and joints. Ipamorelin has one of the best safety profiles among growth hormone secretagogues, as it does not affect cortisol and prolactin levels.
Who is Ipamorelin suitable for?
Ipamorelin is suitable for a wide range of users: athletes for improved recovery and muscle mass gain, people over 30–35 to compensate for the natural decline in growth hormone production, those wanting to improve sleep quality and energy levels, and people seeking better overall body composition (more muscle, less fat). Thanks to its gentle action profile, it is suitable for long-term course use.
Where to order Ipamorelin with delivery to Europe?
Ipamorelin is available for order at peptex.shop with fast delivery across Europe. Original peptide with purity guarantee, secure thermal packaging, payment by card or cryptocurrency. Each order includes usage instructions.
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