Buy PT-141 – Research Peptide | PEPTEX

Chemical information:CAS: 189691-06-3Molecular formula: C50H68N14O10Molecular weight: 1025.18 DaThis entry summarizes published peptide research and laboratory handling notes. Research use only — not for human consumption, diagnostic or therapeutic use. PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide and a non-selective melanocortin receptor agonist. Unlike PDE5 inhibitors such as sildenafil, which act on the peripheral vasculature, PT-141 targets the central nervous system — binding to melanocortin receptors (primarily MC4R) in hypothalamic circuits involved in sexual motivation and arousal. In June 2019 the U.S. Food and Drug Administration approved bremelanotide under the brand name for premenopausal women with acquired hypoactive sexual desire disorder (HSDD). Mechanism of action Activation of MC4R in the medial preoptic area and paraventricular nucleus increases dopamine release in the mesolimbic pathway, which is thought to mediate libido and sexual response independently of peripheral blood flow. Because the effect is upstream of vascular events, research subjects report restoration of interest and arousal rather than simply an erectile response. Evidence from peer-reviewed research The two pivotal Phase 3 RECONNECT trials, published in Obstetrics & Gynecology in 2019, enrolled more than 1,200 premenopausal women and demonstrated statistically significant improvements in desire and reductions in distress compared with placebo. Earlier research in the Journal of Sexual Medicine (2006) had already documented a subjective improvement in sexual response in premenopausal women with arousal disorder after bremelanotide administration. A 2022 review in Neurology International synthesised the safety and efficacy profile across male and female study populations. Typical research protocols In published studies bremelanotide is administered subcutaneously approximately 45 minutes before anticipated sexual activity, at single doses in the low-milligram range. In laboratory-grade use the peptide is reconstituted with bacteriostatic water and loaded into insulin syringes; researchers typically titrate to the lowest effective dose due to transient side-effects such as flushing or mild nausea at higher doses. Quality and purity PEPTEX supplies PT-141 lyophilised from acetate buffer to ≥99% purity verified by HPLC. Each vial is sealed and traceable to its batch certificate. Storage and handling Store lyophilised PT-141 at −20 °C, protected from light, for up to 24 months. After reconstitution with bacteriostatic water, store at 2–8 °C and use within 12 weeks. Discard any vial showing discoloration or particulates. Related research compounds: Bacteriostatic Water. All PEPTEX research peptides ship with batch-specific Certificate of Analysis (HPLC ≥99%). Lyophilized form, EU warehouse, 24-hour dispatch. Research use only (RUO).

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• 10mg — 89 EUR

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